Clinical characteristics of patients with multiple sclerosis according to the registry of the Gomel region

Abstract

Analysis of clinical characteristics of patients with multiple sclerosis according to the data of the Gomel Region register for the period 2017-2020. The register included 633 patients with MS, of which 143 patients were examined (100 women and 43 men, follow-up time: 4 years, average age: 38.9 years, average age of MS debut: 26.5, average EDSS score: 3.75 points, time from the onset of the disease to inclusion in the study: 7.4 years). The primary debut symptoms and clinical picture in the advanced stage of the disease are described, the characteristics of changes on MRI are also compiled, the leading type of course is identified. In patients with MS, at the onset of the disease, most patients have the Uthoff phenomenon and clinical symptoms of motor, sensory, cerebellar disorders. Less often, the debut symptoms were damage to cranial nerves and impaired pelvic organ function. The main ivalidizing symptom in the expanded clinical picture of the disease was the defeat of the pyramidal system and cerebellum.