SPECTRUM OF PATHOGENS OF MAJOR INFECTIOUS COMPLICATIONS IN HOSPITALIZED CIRRHOTIC PATIENTS
Abstract
The aim of the study was to determine of structure of bacterial complications of cirrhosis and antibiotic resistance of pathogens in hospitalized patients with cirrhosis. The structure of etiology of bacterial infections and antibiotic resistance of bacteria in this group is cited. Results: a total 57 samples of ascitic fluid, 29 samples of blood, 21 samples of urine, and 8 samples of sputum has been processed. Were detected 67 cases of bacterial infections (44,4%; 95%CI 36,3-52,7%). The most common causative bacteria in blood and AF microbial analysis were Gram-positive cocci (73%). Urinary tract infections were mainly caused by Enterobacteriaceae's family (75%). The rate of multiresistant bacteria was 18,5% (95%CI 6,3-38,9).
About the Authors
D. . Haurylenka
ГУ "РНПЦ радиационной медицины и экологии человека"
Russian Federation
Russian Federation
N. . Silivontchik
ГУО "Белорусская медицинская академия последипломного образования"
Russian Federation
Russian Federation
N. . Shevchenko
ГУ "РНПЦ радиационной медицины и экологии человека"
Russian Federation
Russian Federation
Y. . Yarets
ГУ "РНПЦ радиационной медицины и экологии человека"
Russian Federation
Russian Federation
References
1. Bacterial infections in liver cirrhosis / M. Navasa [et al.] // Ital J Gastroenterol Hepatol. - 1999. - Vol. 31. - P. 616-625
2. Infections in patients with cirrhosis increase mortality four-fold and should be used in determining prognosis / V. Arvaniti [et al.] // Gastroenterology. - 2010. - Vol. 139. - P. 1246-1256.
3. Sepsis in cirrhosis: Report on the 7th meeting of the international ascites club on behalf the International Ascites Club / F. Wong [et al.] // Gut. - 2005. - Vol. 54. - P. 718-725.
4. Severe sepsis in cirrhosis / T. Gustot [et al.] // Hepatology. - 2009. - Vol. 50. - P. 2022-2033.
5. Prevalence and risk factors of infections by multiresistant bacteria in cirrhosis: A prospective study / J. Fernández [et al.] // Hepatology. - 2012. - Vol. 55. - P. 1551- 1561.
6. High prevalence of antibiotic-resistant bacterial infections among patients with cirrhosis at a US liver center / P. Tandon [et al.] // Clin Gastroenterol Hepatol. - 2012. - Vol. 10. - P. 1291-1298
Review
For citations:
Haurylenka D., Silivontchik N., Shevchenko N., Yarets Y. SPECTRUM OF PATHOGENS OF MAJOR INFECTIOUS COMPLICATIONS IN HOSPITALIZED CIRRHOTIC PATIENTS. Medical and Biological Problems of Life Activity. 2016;(1):150-156. (In Russ.)
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