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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medbio</journal-id><journal-title-group><journal-title xml:lang="ru">Медико-биологические проблемы жизнедеятельности</journal-title><trans-title-group xml:lang="en"><trans-title>Medical and Biological Problems of Life Activity</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2088</issn><publisher><publisher-name>Республиканский научно-практический центр радиационной медицины и экологии человека</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medbio-155</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>СПЕКТР ВОЗБУДИТЕЛЕЙ ОСНОВНЫХ ИНФЕКЦИОННЫХ ОСЛОЖНЕНИЙ У ГОСПИТАЛИЗИРОВАННЫХ ПАЦИЕНТОВ С ЦИРРОЗОМ ПЕЧЕНИ</article-title><trans-title-group xml:lang="en"><trans-title>SPECTRUM OF PATHOGENS OF MAJOR INFECTIOUS COMPLICATIONS IN HOSPITALIZED CIRRHOTIC PATIENTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гавриленко</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Haurylenka</surname><given-names>D. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Силивончик</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Silivontchik</surname><given-names>N. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевченко</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevchenko</surname><given-names>N. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярец</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yarets</surname><given-names>Y. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГУ "РНПЦ радиационной медицины и экологии человека"</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>ГУО "Белорусская медицинская академия последипломного образования"</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>02</day><month>03</month><year>2023</year></pub-date><volume>0</volume><issue>1</issue><fpage>150</fpage><lpage>156</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гавриленко Д.И., Силивончик Н.Н., Шевченко Н.И., Ярец Ю.И., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Гавриленко Д.И., Силивончик Н.Н., Шевченко Н.И., Ярец Ю.И.</copyright-holder><copyright-holder xml:lang="en">Haurylenka D..., Silivontchik N..., Shevchenko N..., Yarets Y...</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medbio.ejournal.by/jour/article/view/155">https://medbio.ejournal.by/jour/article/view/155</self-uri><abstract><p>Целью данной работы было определение этиологической структуры основных инфекционных осложнений и анализ антибиотикорезистентности возбудителей инфекций в группе госпитализированных пациентов с циррозом печени. Проанализирована этиологическая структура инфекционных осложнений и антибиотикорезистентность бактериальных возбудителей инфекций в данной группе пациентов. Выполнено микробиологическое исследование 57 образцов асцитической жидкости, 29 образцов крови, 21 образца мочи, 8 образцов мокроты. Бактериальные инфекции обнаружены у 67 пациентов (44,4%; 95% ДИ 36,3-52,7%). Основными бактериальными агентами, выделенными при исследовании крови и АЖ, были грамположительные микроорганизмы (73%), представленные в основном семейством Staphylococcaceae. Инфекции мочевых путей в основном были вызваны грамотрицательными бактериями (75%), с доминированием семейства Enterobacteriaceae. Частота выявления полирезистентных бактерий у госпитализированных пациентов с декомпенсированным циррозом печени составила 18,5% (95% ДИ 6,3-38,9).</p></abstract><trans-abstract xml:lang="en"><p>The aim of the study was to determine of structure of bacterial complications of cirrhosis and antibiotic resistance of pathogens in hospitalized patients with cirrhosis. The structure of etiology of bacterial infections and antibiotic resistance of bacteria in this group is cited. Results: a total 57 samples of ascitic fluid, 29 samples of blood, 21 samples of urine, and 8 samples of sputum has been processed. Were detected 67 cases of bacterial infections (44,4%; 95%CI 36,3-52,7%). The most common causative bacteria in blood and AF microbial analysis were Gram-positive cocci (73%). Urinary tract infections were mainly caused by Enterobacteriaceae's family (75%). The rate of multiresistant bacteria was 18,5% (95%CI 6,3-38,9).</p></trans-abstract><kwd-group xml:lang="ru"><kwd>антибиотикорезистентность</kwd><kwd>цирроз печени</kwd><kwd>полирезистентные штаммы</kwd><kwd>спонтанный бактериальный перитонит</kwd><kwd>antibiotic resistance</kwd><kwd>cirrhosis</kwd><kwd>multiresistant organisms</kwd><kwd>spontaneous bacterial peritonitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bacterial infections in liver cirrhosis / M. Navasa [et al.] // Ital J Gastroenterol Hepatol. - 1999. - Vol. 31. - P. 616-625</mixed-citation><mixed-citation xml:lang="en">Bacterial infections in liver cirrhosis / M. 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