THE ANALYSIS OF CYTOKINE INDICES IN THE TREATMENT OF BENIGN CYSTIC OVARIAN TUMORS
Abstract
The article provides analysis data of cytokine levels in blood serum within the patients with cystic benign tumors of the ovaries as well as changes of IL-2 , IL-8 cytokines and TNF during anti-inflammatory therapy. Examinations and treatment are conducted on the basis of clinical and gynecology departments of SI "RRC for RM&HE". 98 patients of the major group (group1) and 30 patients of monitoring group (group 2) were examined. Anti- inflammatory treatment was provided for the patients of the major group. There were detected statistically significant changes of cytokine level after the treatment and the differences in cytokine levels within the patients with tumorous neoplasms and endometrioid ovarian cysts. Using ROC - analysis it was found out that the most informative in identifying patients with endometrial cysts were the indices of CRP and TNF. Thus, the changes in cytokine levels and CRP are indicative during outpatient stage and allow holding a differentiated approach to the diagnosis and treatment of benign cystic ovarian tumors.
About the Authors
O. V. Murashko
ГУ "РНПЦ радиационной медицины и экологии человека"
Russian Federation
Russian Federation
O. K. Doronina
УО "Белорусский государственный медицинский университет"
Russian Federation
Russian Federation
Y. I. Yarets
ГУ "РНПЦ радиационной медицины и экологии человека"
Russian Federation
Russian Federation
N. I. Shevchenko
ГУ "РНПЦ радиационной медицины и экологии человека"
Russian Federation
Russian Federation
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Review
For citations:
Murashko O.V., Doronina O.K., Yarets Y.I., Shevchenko N.I. THE ANALYSIS OF CYTOKINE INDICES IN THE TREATMENT OF BENIGN CYSTIC OVARIAN TUMORS. Medical and Biological Problems of Life Activity. 2016;(2):78-84. (In Russ.)
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