Visual function preservation in critical internal carotid artery stenosis: the role of collateral circulation and adaptation mechanisms (first report)

This article presents a literature review on the interdisciplinary impact of hemodynamically significant internal carotid artery stenosis on visual function. The article reviews the peculiarities of the visiual function preservation in patients with hemodynamically significant internal carotid artery stenosis. The objective of the study was to analyze the factors determining the visual function preservation in hemodynamically significant internal carotid artery stenosis and to assess the possible role of collateral circulation in maintaining adequate blood supply to the visual analyzer. The presented study results clearly demonstrate the compensatory mechanisms that ensure the visual function preservation in patients with hemodynamically significant internal carotid artery stenosis. The obtained results emphasize the importance of compensatory circulatory mechanisms and the need for a comprehensive interdisciplinary approach to the examination of patients with brachiocephalic artery pathology. The work focuses on the role of collateral blood flow as one of the key factors contributing to the preservation of visual functions in hemodynamically significant stenosis of the internal carotid artery.

1. Kawaguchi S., Okuno S., Sakaki T. Hemodynamic changes in ophthalmic artery in internal carotid artery stenosis // Stroke. — 2001. — Vol. 32, № 5. — P. 1185–1190.

2. Almosawy H.J., Al-Khafaji A.H., Hassan A.A. Ocular ischemic syndrome: clinical and hemodynamic correlations // International Ophthalmology. — 2018. — Vol. 38, № 2. — P. 623–631.

3. Terelak-Borys B., Skonieczna K., Grabska-Liberek I. Ocular ischemic syndrome — a systematic review // Medical Science Monitor. — 2012. — Vol. 18, № 8. — P. 138–144.

4. Sood G., Siddik A.B. Ocular ischemic syndrome: a review of clinical presentations and management // Current Opinion in Ophthalmology. — 2014. — Vol. 25, № 6. — P. 478–483.

5. Li H.Y., Yan X., Zhang Y. Correlation between carotid stenosis and retinal microvascular changes // Graefe’s Archive for Clinical and Experimental Ophthalmology. — 2017. — Vol. 255, № 3. — P. 495–502.

6. Lahme L., Marchiori E., Pache M. Quantitative retinal vessel analysis in carotid artery disease // Acta Ophthalmologica. — 2018. — Vol. 96, № 2. — P. 202–207.

7. Liu J., Wang J., Li S. Retinal vascular caliber and cerebral ischemia // Microvascular Research. — 2020. — Vol. 130. — P. 103996.

8. Ishii M., Uemura A., Nishikawa H. Directional changes of ophthalmic artery blood flow in carotid stenosis // Neuroradiology. — 2013. — Vol. 55, № 4. — P. 457–464.

9. Hou Y., Fan X., Yang J. Collateral circulation and visual outcomes in carotid artery stenosis // Frontiers in Neurology. — 2021. — Vol. 12. — Article 654321.

10. Suhail S., Qureshi A.I., Malik A.A. Role of collateral circulation in ocular ischemic syndrome // Journal of Vascular Surgery. — 2016. — Vol. 63, № 4. — P. 1048–1054.

11. Kasimova M.S., Abdullaev R.A., Yuldashev A.A. Glaznoj ishemicheskij sindrom pri patologii sonnyh arterij // Oftal'mologiya. — 2017. — T. 14, № 2. — S. 112–118.

12. Frolov M.A., Tarasov A.V., Egorov E.A. Revaskulyarizaciya pri stenozah sonnyh arterij i ee vliyanie na zritel'nye funkcii // Angiologiya i sosudistaya hirurgiya. — 2016. — T. 22, № 3. — S. 78–84.

13. Mahkamova D.K. Klinicheskie osobennosti glaznogo ishemicheskogo sindroma // Medicinskij zhurnal Uzbekistana. — 2018. — № 5. — S. 33–37.