Risks of clinical manifestation of diabetes mellitus type 2 in the working-age population

Abstract

An epidemiological study found that the incidence of type 2 diabetes melitus in men and women increases with increasing biological age, with an earlier onset (by 7–10 years) in men. The peak of DM type 2 in men was observed between the ages of 35 and 39, and in women, between the ages of 45 and 49. Among patients aged 34-39 who did not have a verified diagnosis of DM type 2 at the time of screening, 8.1% had a lipid profile shift toward atherogenesis. Increases in random glycemia above target values were observed in 0,4% of those examined, and glycated hemoglobin levels above target values occurred in 1,8%, demanding establishment of a diagnosis of prediabetes or DM type 2. These biochemical changes indicate an asymptomatic course of DM type 2 and necessity of monitoring of glycated hemoglobin and lipid profile. Patients with a lipid profile shifting towards atherogenesis should be considered as a risk group for the development of DM type 2.