Psychophysiological adaptation of two patients with acute radiation sickness and leukemia affected in the accident at Chernobyl NPP

Assessment of psychophysiological adaptation of two patients with severe ARS and moderate ARS and leukemia, who suffered in the accident at Chernobyl NPP, according to the data of their individual mental adaptation and stages of the hematological syndrome.Two patients, former workers of the emergency shift of the Chernobyl NPP, were examined. One of them performed the duties of an engineer (Patient No. 1, 1961), the second - deputy head of the turbine shop (Patient No. 2, 1950). They are 04/26/1986. were subjected to acute external relatively uniform gamma-beta irradiation due to the accident at Chernobyl NPP. Patient No. 1 received acute radiation sickness of III degree of severity, multiple radiation burns of I-II degrees (40%) and III-IV degrees (15%) of the body surface. Patient No. 2 - ARS II degree of severity and oropharyngeal syndrome I degree. The radiation dose, according to cytogenetic studies, was 4,3 Gy (Patient No. 1) and 3,4 Gy (Patient No. 2). Patient No. 1 in January 2007 was diagnosed with chronic myeloid leukemia PH-positive in the phase of acceleration. Patient No. 2 - in June 2016 AML, transformation from myelodysplastic syndrome (MDS). Despite the ongoing therapy, death in patient No. 1 occurred in November 2008, in patient No. 2 - in March 2017.Psychophysiological research was carried out using the automated software and methodological complex «Expert», designed to study the personality traits of a person, cognitive and intellectual personality traits.The individual personality traits were determined in two patients in the form of asthenic depression with depressive-hypochondriacal tendencies in one patient and a demonstrative type of psychophysiological adaptation disorder with pronounced hypochondria and a tendency to anxiety-depressive type of behavior in the other.Individual personality traits are represented by two types of impairment of psychophysiological adaptation: the type of asthenic depression and the demonstrative type of impairment of psychophysiological adaptation.

acute radiation sickness, local radiation injuries, acute leukemia, chronic myeloid leukemia

1. Березин, Ф.Б. Методика многостороннего исследования личности. Структура, основы интерпретации, некоторые области применения / Ф.Б. Березин, М.П. Мирошников, Е.Д. Соколова// Предисл. Т. Барлас. - 3-е изд., испр. и доп. - М.: «БЕРЕЗИН ФЕЛИКС БОРИСОВИЧ», 2011. - 320 с.

2. Соколова, Е.Д. Клинические аспекты нарушений психической адаптации. Психическая адаптация человека в условиях Севера / Е.Д. Соколова, В.Ф. Калачев, А.А. Долныкова. - Владивосток, 1980. - С. 77-96.

3. Короленко, Ц.П. Психофизиология человека в экстремальных условиях / Ц.П. Короленко. - Л., 1978. - 150 с.

4. Изучение последствий ядерных взрывов / Под ред. А.И. Бурназяна и А.К. Гуськовой, пер. с англ. - М.: Медицина, 1964. - 480 с.

5. Онкогематологические заболевания у перенесших острую лучевую болезнь / Л.А. Суворова [и др.] // Мед. радиол. и радиац. безопасность. - 2008. - Т. 53, №5. - С. 26-34.

6. Studies of the mortality of atomic bomb survivors. Rep. 12, Part 1 Cancer: 1950-1990 / D.A. Pierce [et al.] // Radiat. Res. - 1996. - Vol. 146, №1. - P. 1-27.

7. Leukemia incidence in the atomic bomb survivor life span study, 195087 / D.L. Preston [et al.] // In: Proceed. of Intern. Conference on Radiation Effects and Protection, March 18-20, 1992. - Japan Atomic Energy Research. Inst., 1992. - P. 103-107.

8. Ichimaru, M. A review of thirty years study of Hiroshima and Nagasaki atomic bomb survivors / M. Ichimaru, T. Ishimaru //j. Radiat. Res. - 1975. - Suppl. - P. 89-96.

9. Wolff1, R. High Prevalence of Chronic Lymphocytic Leukemia and B-cell Lymphomas in Nuclear Workers after the Incorporation of Alpha Emitters: Case Report and Review of the Literature / R. Wolff1, R. Grentzel-Beyme, I. Schmitz-Feuerhake // RAD Conference Proceedings. - 2018. - vol. 3, P. 143-148, DOI: 10.21175/RadProc.2018.31www.rad-proceedings.org.