Humoral factors of immunity in children living in ecologically unfavorable regions in the Republic of Armenia
https://doi.org/10.58708/2074-2088.2024-1(31)-81-87
Abstract
The influence of the environment on the immune system function can lead to the development of an environmentally conditioned secondary immunodeficiency. The importance of searching for immunological markers to assess the impact of environmental factors on the health of the child population can be expressed in the results of immunological studies and can show the degree of influence of environmental pollution on the child’s health and condition. This article analyzes the humoral immune factors in children living in the ecologically disadvantaged Ararat region of the Republic of Armenia. A decrease of the IgM and IgG concentrations in saliva was found in combination with an increase of the total IgE and C3a component of the complement system levels in the blood serum of the examined children, which indicates the manifestation of environmental immunosuppression and can serve as a marker of the state of the immune system under the influence of various adverse environmental factors.
About the Authors
T. Astabatsyan
Армянский медицинский институт ; Международный государственный экологический институт им. А.Д. Сахарова Белорусского государственного университета
Armenia
Armenia
D. B. Nizheharodava
Международный государственный экологический институт им. А.Д. Сахарова Белорусского государственного университета
Belarus
Belarus
V. Grigoryan
НИИ физиологии имени Л. Орбели НАН
Armenia
Armenia
Z. Karabekyan
НИИ физиологии имени Л. Орбели НАН
Armenia
Armenia
M. M. Zafranskaya
Международный государственный экологический институт им. А.Д. Сахарова Белорусского государственного университета
Belarus
Belarus
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For citations:
Astabatsyan T., Nizheharodava D.B., Grigoryan V., Karabekyan Z., Zafranskaya M.M. Humoral factors of immunity in children living in ecologically unfavorable regions in the Republic of Armenia. Medical and Biological Problems of Life Activity. 2024;(1):81-87. (In Russ.) https://doi.org/10.58708/2074-2088.2024-1(31)-81-87
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