Etiology and pathogenesis of pelvic floor dysfunction (literature review)
https://doi.org/10.58708/2074-2088.2024-1(31)-16-21
Abstract
Pelvic floor dysfunction (PFD) in women includes conditions such as vaginal relaxation syndrome (VRS), pelvic organ prolapse (POP), urinary and fecal incontinence, obstructed defecation, and sexual dysfunction. Etiopathogenesis is associated with disorders of the pelvic floor fixing apparatus that arise due to traumatic childbirth, genetic changes in the structure of connective tissue (polymorphism of the gene for connective tissue enzymes NAT2). Techniques used to diagnose pelvic floor injuries include x-rays, computed tomography, magnetic resonance imaging (MRI), and ultrasound. In this publication, we presented an overview of the most relevant and recent data on the etiopathogenesis, diagnosis of DTD.
About the Authors
O. V. Murashko
ГУ «РНПЦ радиационной медицины и экологии человека»
Belarus
Belarus
A. S. Podgornaya
ГУ «РНПЦ радиационной медицины и экологии человека»
Belarus
Belarus
A. Y. Zakharko
ГУ «РНПЦ радиационной медицины и экологии человека»
Belarus
Belarus
References
1. Self-Reported Vaginal Laxity-Prevalence, Impact, and Associated Symptoms in Women Attending a Urogynecology Clinic / P. Campbell [et al.] // J Sexual Medicine. – 2018. – Vol. 15(11). – P. 1515-1517. DOI: 10.1016/j.jsxm.2018.08.015.
2. Alexander, J.W. Is vaginal laxity anearly symptom of pelvic organ prolapse? / J.W. Alexander, M. Gillor, H.P. Dietz // International Urogynecology Journal. – 2021. DOI: 10.1007/s00192-021-04927-3
3. Vaginal laxity: what does this symptom mean? / H.P. Dietz [et al.] // International Urogynecology Journal. – 2018. – Vol. 29(5). – P. 723-728. DOI: 10.1007/s00192-017-3426-0.
4. Pelvic organ prolapse in nulliparae / H.P. Dietz [et al.] // Aust N Z J Obstet Gynaecol. – 2022. – Vol. 62(3). – P. 420-425. doi: 10.1111/ajo.13481.
5. Prevalence, risk factors, and predictors of pelvic organ prolapse: a community-based study / J. Awwad [et al.] // Menopause. – 2012. – Vol. 19(11). – P. 1235-1241. DOI: 10.1097/gme.0b013e31826d2d94
6. Клиническая эффективность вагинального тренажера в лечении несостоятельности мышц тазового дна у женщин пожилого возраста / О.С. Короткевич [и др.] // Фундаментальная и клиническая медицина. – 2018. – Т. 3(4). – С. 32-38. eLIBRARY ID: 36689902.
7. Petros, P. An integral theory of female urinary incontinence. Experimental and clinical considerations / P. Petros, U. Ulmsten // Acta Obstet Gynecol Scand. – 1990. – Vol. 69. – P. 1-37.
8. Шкарупа, Д.Д. Женская тазовая медицина и реконструктивная хирургия / Д.Д. Шкарупа, Н.Д. Кубин. – М.: «МЕДпресс-информ», 2022, – С. 35-37.
9. Hallock, J.L. The epidemiology of pelvic floor disorders and childbirth: an update / J.L. Hallock, V.L. Handa // Obstet Gynecol Clin North Am. – 2016. – Vol. 43(1). – P. 1–13. DOI: 10.1016/j.ogc.2015.10.008.
10. Nevler, A. Epidemiology of anal incontinence and evaluation of the severity of symptoms / A. Nevler // Gastroenterology Report. – 2014. – Vol. 2(2). – P. 79-84. DOI: 10.1093/gastro/gou005.
11. Biomechanics of the female pelvic floor / M. Alperin, K. Debes, L. Hoyte, M. Damaser, eds. – Academic press, 2016. – 437 р.
12. Consultation about urinary and faecal incontinence in the year after childbirth: a cohort study / S. Brown [et al.] // BJOG. – 2015. – Vol. 122(7). – P. 954-962. DOI:10.1111/1471-0528.12963
13. Non-Invasive Determination of LOXL1 and Fibulin-5 Levels in the Vaginal Secretions of Women with and Without Pelvic Organ Prolapse / B. Garcia [et al.] // JMedResSurg. – 2021. – Vol. 2(2). DOI: 10.52916/jmrs214042.
14. Дисфункция тазового дна у женщин в аспекте генетических исследований / Л.В. Акуленко [и др.] // Урология. – 2017. – Т. 1. – С. 76-81.
15. Elbiss, H.M. Prevalence, risk factors and severity of symptoms of pelvic organ prolapse among Emirati women / H.M. Elbiss, N. Osman, F.T. Hammad // Multicenter Study BMC Urol. – 2015. – Vol. 15. – no. art. 66. doi: 10.1186/s12894-015-0062-1.
16. A systematicreview of clinical studies on hereditary factors in pelvic organprolapse / S.L. Lince [et al.] // Int. Urogynecol. J. – 2012. – Vol. 23(10). – P. 1327-1336. DOI: 10.1007/s00192-012-1704-4.
17. Alcalay, M. Family history associated with pelvicorgan prolapse in young women / M. Alcalay, K. Stav, V.H. Eisenberg // Int Urogynecol J. – 2015. – Vol. 26(12). – P. 1773-1776. DOI: 10.1007/s00192-015-2779-5.
18. Генетические основы патобиохимических особенностей соединительной ткани больных с пролапсом гениталий / В.Е. Радзинский [и др.] // Гинекология. – 2017. – Т. 19, №6. – С. 38-42. DOI: 10.26442/2079-5696_19.6.38-42.
19. Хапачева, С.Ю. Факторы риска дисфункции тазового дна икомпьютерная программа его прогнозирования у женщин в послеродовом периоде / С.Ю. Хапачева, Н.В. Артымук // Медицина в Кузбассе. – 2021. – Т. 2. – С. 59-64. DOI: 10.24411/2687-0053-2021-10024.
20. Obesity andpelvic organ prolapse / U.J. Lee [et al.] // CurrOpin Urol. – 2017. – Vol. 27. – P. 428-434. DOI: 10.1097/MOU.0000000000000428.
21. How do deliverymode and parity affect pelvic organ prolapse? / A.O. Yeniel [et al.] // Acta Obstet Gynecol Scand. – 2013. – Vol. 92(7). – P. 847-851. DOI: 10.1111/aogs.12129
22. Minassian, V.A. Urinary incontinence in women: variation in prevalence estimates and risk factors / V.A. Minassian, W.F. Stevart, G.C. Wood // Obstet. Gynecol. – 2008. – Vol. 111 (2Pt 1). – P. 324-331.
23. Risk factors for urinary incontinence among women aged 60 or over with hypertension in Taiwan / K.-M. Chang [et al.] // Taiwan J. Obstet. Gynecol. – 2014. – Vol. 53(2). – P. 183-186.
24. John, G. Urinary incontinenceand cardiovascular disease a narrative review / G. John // Int Urogynecol. J. – 2020. – Vol. 31(5). – P. 857-863.
25. Коршунов, М.Ю. Опросник пд-кж – валидированный способ оценки симптомов дисфункций тазового дна и качества жизни у пациенток с пролапсом тазовых органов / М.Ю. Коршунов, Е.И. Сазыкина // Журнал Акушерства и Женских болезней. – 2008. – Т. LVII, выпуск 3. – С. 86-91.
26. The standardization of terminology of female pelvic organprolapse and pelvic floor dysfunction / C.B. Richard [et al.] // Am J Obstet Gynecol. – 1996. – Vol. 175. P. 10-17. DOI: 10.1016/s0002-9378(96)70243-0
27. Современные методы оценки функции и силы мышц тазового дна у женщин / Г.Б. Дикке [и др.] // Медицинский алфавит. – 2019. № 1(1). – С. 80-85. DOI: 10.33667/2078-5631-2019-1-1(376)-80-85.
28. Pad weight testing in the evaluation of urinary incontinence / J. Krhut [et al.] // Neurourol. Urodyn. – 2014. – Vol. 33(5). – P. 507-510.
29. Wong, Jennifer W.H. Urinary Incontinence and Pelvic Organ Prolapse / Jennifer W.H. Wong, O. Ramm // Clin ObstetGynecol. – 2021. – Vol. 64(2). – P. 314-320. DOI: 10.1097/GRF.0000000000000615.
30. Ультразвуковая диагностика пролапса гениталий и недержания мочи у женщин / М.А. Чечнева [и др.]. – М.: МЕДпресс-информ, 2019. – C. 17-19
31. Dietz, H.P. Ultrasound in the assessment of pelvic organ prolapse / H.P. Dietz // BestPract Res Clin ObstetGynaecol. – 2019. – Vol. 54. – P. 12-30. DOI: 10.1016/j.bpobgyn.2018.06.006
32. Khatri, G. MR Imaging of the Pelvic Floor / G. Khatri, A.D. de Leon, M.E. Lockhart // Magn Reson Imaging Clin N Am. – 2017. – Vol. 25(3). – P. 457-480. DOI: 10.1016/j.mric.2017.03.003
33. Female pelvic organ prolaps using pessaries: systematic revier / S.C. DeAlbuquerque [et al.] // Int. Urogynecol. J. – 2016. – Vol. 27(12). – P. 1797-1803.
Review
For citations:
Murashko O.V., Podgornaya A.S., Zakharko A.Y. Etiology and pathogenesis of pelvic floor dysfunction (literature review). Medical and Biological Problems of Life Activity. 2024;(1):16-21. (In Russ.) https://doi.org/10.58708/2074-2088.2024-1(31)-16-21
Views: 95
Email this article 