Diagnostic and predictive capabilities pathological remodeling of the left ventricular myocardium
Abstract
As a result of the study, the differences between patients with arterial hypertension, atherosclerotic and postinfarction cardiosclerosis were determined in terms of the levels of biomarkers of myocardial fibrosis and inflammation, blood lipid spectrum, and renin. The indicators of ultrasound examination of the heart, carried out both according to the standard technique and using tissue myocardial Doppler sonography and 2D Speckle Tracking technology, have been analyzed. A diagnostic model for predicting pathological remodeling of the left ventricle of the heart is proposed.
About the Authors
A. V. Korotaev
ГУ «РНПЦ радиационной медицины и экологии человека»
Russian Federation
Russian Federation
E. P. Naumenko
ГУ «РНПЦ радиационной медицины и экологии человека»
Russian Federation
Russian Federation
L. E. Korotaeva
ГУ «РНПЦ радиационной медицины и экологии человека»
Russian Federation
Russian Federation
References
1. Преображенский, Д.В. Гипертрофия левого желудочка при гипертонической болезни. Часть II. Прогностическое значение гипертрофии левого желудочка / Д.В. Преображенский, Б.А. Сидоренко, М.Н. Алехин // Кардиология. - 2008. - №11. - С. 98-101.
2. Нечесова, Т.А. Ремоделирование левого желудочка: патогенез и методы оценки / Т.А. Нечесова, И.Ю. Коробко, Н.И. Кузнецова // Медицинские новости. - 2008. - №11. - С. 7-13.
3. Глезер, М. Г. Ремоделирование левого желудочка: патогенез и методы оценки / М.Г. Глезер // Клиническая геронтология. - 2000. - №1. - С. 33-43.
4. Cohn, J.N. Cardiac remodeling - concepts and clinical implications: a consensus paper from an international forum on cardiac remodeling. Behalf of an International Forum on Cardiac Remodeling /j.N. Cohn, R. Ferrari, N. Sharpe //j. Am. Coll. Cardiol. - 2000. - Vol. 35, №3. - P. 569-582. doi: 10.1016/s0735-1097(99)00630-0.
5. Vantrimpont, P. Two-year time course and significance of neurohumoral activation in the Survival and Ventricular Enlargement (SAVE) Study / P. Vantrimpont [et al.] // Eur. Heart J. - 1998. - Vol. 19. - P. 1552-1563.
6. Yousef, Z.R. Postinfarction left ventricular remodeling: a pathophysiological and therapeutic review / Z.R. Yousef, S.R. Redwood, M.S. Marber // Cardiovascular Drugs and Therapy. - 2000. - Vol. 14. - P. 243-252.
7. Рекомендации по количественной оценке структуры и функции камер сердца // Российский кардиологический журнал. - 2012. - № 3. - С. 1-28.
8. Two-dimentional strain - a novel software for real time quantitative echocardiographic assessment of myocardial function / M. Leitman [et al.] //j. Am. Soc. Echocardiogr. - 2004. - Vol. 17. - P. 1021-1029.
9. Целуйко, В.И. Оценка деформации миокарда левого желудочка в клинической практике / В.И. Целуйко, К.Ю. Киношенко, Н.Е. Мищук // Фармакотерапия. - 2004. - №9. - С. 52-56.
10. Brown, J. Use of myocardial strain to assess global left ventricular function: a comparison with cardiac magnetic resonance and 3-dimensional echocardiography /j. Brown, C. Jenkins, T.H. Marwick // Am. Heart J. - 2009. - Vol. 157, №1. - P. 101-105.
11. Stanton, T. Prediction of all-cause mortality from global longitudinal speckle strain: comparison with ejection fraction and wall motion scoring / T. Stanton, R. Leano, T.H. Marwick // Circ. Cardiovasc. Imaging. - 2009. - Vol. 2, №5. - P. 356-364.
12. Left ventricular hypertrophy causes different changes in longitudinal, radial, and circumferential mechanics in patients with hypertension: a two-dimensional speckle tracking study / H. Kouzu [et al.] //j. Am. Soc. Echocardiogr. - 2011. - Vol. 24. - P. 192-199.
13. Investigation on myocardial systolic multi-dimensional deformation in hypertension patients with left ventricular remodeling by two-dimensional strain echocardiography / M.Y. Lin [et al.] // Chinese J. Ultrasound Med. - 2012. - Vol. 28, №5. - P. 421-441.
14. Tissue Doppler Imaging differentiate sphysiological from pathological pressure overload left ventricular hypertrophy in rats / G. Derumeaux [et al.] // Circulation. - 2002. - Vol. 105. - P. 1602-1608.
Review
For citations:
Korotaev A.V., Naumenko E.P., Korotaeva L.E. Diagnostic and predictive capabilities pathological remodeling of the left ventricular myocardium. Medical and Biological Problems of Life Activity. 2021;(1):122-129. (In Russ.)
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