Assessment of the Influence of Perinatal and Intranatal Factors on the Number of TREC/ KREC Copies in Premature Infants
Abstract
This study quantified T and B cell receptor DNA ring fragments (TREC and KREC) in the peripheral blood of 115 preterm infants with gestational ages of 23,4-37,0 weeks. It has been shown that perinatal and intaranatal factors, such as anamnestic, obstetric and gynecological, complications of the course of pregnancy, type of delivery, singleton and multiple pregnancies do not have a significant effect on the number of TREC/KREC copies in the peripheral blood of premature infants, therefore, do not have a significant effect on functional state of immunity during the neonatal period.
About the Authors
E. A. Polyakova
ГУ «РНПЦ детской онкологии, гематологии и иммунологии»
Russian Federation
Russian Federation
S. A. Beresten
ГУ «РНПЦ «Мать и дитя»
Russian Federation
Russian Federation
M. V. Stegantseva
ГУ «РНПЦ детской онкологии, гематологии и иммунологии»
Russian Federation
Russian Federation
I. E. Guryanova
ГУ «РНПЦ детской онкологии, гематологии и иммунологии»
Russian Federation
Russian Federation
D. V. Lutsckovich
ГУ «РНПЦ детской онкологии, гематологии и иммунологии»
Russian Federation
Russian Federation
M. V. Belevtsev
ГУ «РНПЦ детской онкологии, гематологии и иммунологии»
Russian Federation
Russian Federation
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Review
For citations:
Polyakova E.A., Beresten S.A., Stegantseva M.V., Guryanova I.E., Lutsckovich D.V., Belevtsev M.V. Assessment of the Influence of Perinatal and Intranatal Factors on the Number of TREC/ KREC Copies in Premature Infants. Medical and Biological Problems of Life Activity. 2021;(2):121-127. (In Russ.)
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