Acute on chronic liver failure
Abstract
Acute on chronic liver failure - a new clinical syndrome characterized by acute decompensation in patients with chronic liver disease, leading to the development of multiple organ failure and is characterized by a high mortality rate. From a pathophysiological point of view, based on the development of this syndrome is excessive systemic inflammatory response to the provocation. The extent of the immune response and the severity of organ failure determines the outcome of patients with acute on chronic liver failure. Most often diagnosed in young patients with active alcoholism, reactivation of hepatitis B, severe in patients without decompensated cirrhosis history.
About the Authors
A. . Kravchenko
ГУО «Гомельский государственный медицинский университет», г. Гомель, Беларусь
Russian Federation
Russian Federation
E. . Malaeva
ГУО «Гомельский государственный медицинский университет», г. Гомель, Беларусь
Russian Federation
Russian Federation
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Review
For citations:
Kravchenko A., Malaeva E. Acute on chronic liver failure. Medical and Biological Problems of Life Activity. 2017;(1):6-12. (In Russ.)
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