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Ultrastructural features of the stapes in patients with otosclerosis

Abstract

The analysis of ultrastructural changes in stapes (pedicles and head) of 18 patients with otosclerosis was carried out. The material for the study was taken during the surgical treatment of the disease (stapedoplasty). The structural changes in stapes were found: focal changes in the bone tissue were characteristic of the active process of resorption and lysis with osteocytes activation, as well as manifestations of active mineralization of bone, the absence of its restructuring into the classic lamellar bone, and foci of abnormal osteogenesis. This study showed ultrastructural changes in stapes in patients with otosclerosis.

About the Authors

N. . Greben
ГУ «РНПЦ оториноларингологии»
Russian Federation


A. . Malets
ГУ «РНПЦ оториноларингологии»
Russian Federation


S. . Ryabceva
Институт физиологии Национальной академии наук Беларуси
Russian Federation


A. . Poradovsky
ГУ «РНПЦ оториноларингологии»
Russian Federation


H. . Stashkevich
ГУ «РНПЦ оториноларингологии»
Russian Federation


I. . Siamionik
Институт физиологии Национальной академии наук Беларуси
Russian Federation


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Review

For citations:


Greben N., Malets A., Ryabceva S., Poradovsky A., Stashkevich H., Siamionik I. Ultrastructural features of the stapes in patients with otosclerosis. Medical and Biological Problems of Life Activity. 2022;(2):60-65. (In Russ.)

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ISSN 2074-2088 (Print)