Microglia of the brain: structural and functional characteristics of cells (literature review)
Abstract
The aim of this literature review is to summarize current data on the morpho-functional characteristics of microglia. The article presents a modern view on the role, function and histological characteristics of microglial cells with an emphasis on the transformation of cells during their activation and dystrophic changes. Several morphotypes of microglial cells are described depending on their functional activity. Variants of dystrophic changes in microglial cells, which are more common in neurodegenerative diseases, are presented.
About the Authors
A. O. Parashchenko
ГНУ «Институт физиологии Национальной академии наук Беларуси»
Russian Federation
Russian Federation
M. A. Korneeva
ГНУ «Институт физиологии Национальной академии наук Беларуси»
Russian Federation
Russian Federation
I. A. Siamionik
ГНУ «Институт физиологии Национальной академии наук Беларуси»
Russian Federation
Russian Federation
S. N. Ryabtseva
ГНУ «Институт физиологии Национальной академии наук Беларуси»
Russian Federation
Russian Federation
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Review
For citations:
Parashchenko A.O., Korneeva M.A., Siamionik I.A., Ryabtseva S.N. Microglia of the brain: structural and functional characteristics of cells (literature review). Medical and Biological Problems of Life Activity. 2022;(2):12-19. (In Russ.)
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