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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medbio</journal-id><journal-title-group><journal-title xml:lang="ru">Медико-биологические проблемы жизнедеятельности</journal-title><trans-title-group xml:lang="en"><trans-title>Medical and Biological Problems of Life Activity</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2088</issn><publisher><publisher-name>Республиканский научно-практический центр радиационной медицины и экологии человека</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medbio-79</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>КЛИНИКО-ФУНКЦИОНАЛЬНЫЕ ОСОБЕННОСТИ ПАЦИЕНТОВ С АТЕРОГЕННЫМИ ДИСЛИПИДЕМИЯМИ</article-title><trans-title-group xml:lang="en"><trans-title>CLINICAL AND FUNCTIONAL CHARACTERS OF THE PATIENTS WITH ATHEROGENIC DYSLIPIDEMIA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коротаев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Korotaev</surname><given-names>A. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Силин</surname><given-names>А. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Silin</surname><given-names>A. E.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Козловская</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kozlovskaya</surname><given-names>T. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Науменко</surname><given-names>Е. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Naumenko</surname><given-names>E. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гордиенко</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gordienkoo</surname><given-names>V. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартинков</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Martinkov</surname><given-names>V. N.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Силина</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Silina</surname><given-names>A. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тропашко</surname><given-names>И. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Tropashko</surname><given-names>I. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мартыненко</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Martynenko</surname><given-names>S. M.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГУ "РНПЦ радиационной медицины и экологии человека"</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>02</day><month>03</month><year>2023</year></pub-date><volume>0</volume><issue>2</issue><fpage>116</fpage><lpage>119</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Коротаев А.В., Силин А.Е., Козловская Т.В., Науменко Е.П., Гордиенко В.В., Мартинков В.Н., Силина А.А., Тропашко И.Б., Мартыненко С.М., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Коротаев А.В., Силин А.Е., Козловская Т.В., Науменко Е.П., Гордиенко В.В., Мартинков В.Н., Силина А.А., Тропашко И.Б., Мартыненко С.М.</copyright-holder><copyright-holder xml:lang="en">Korotaev A.V., Silin A.E., Kozlovskaya T.V., Naumenko E.P., Gordienkoo V.V., Martinkov V.N., Silina A.A., Tropashko I.B., Martynenko S.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medbio.ejournal.by/jour/article/view/79">https://medbio.ejournal.by/jour/article/view/79</self-uri><abstract><p>В работе представлены результаты исследования клинических, лабораторных и инструментальных данных у 162 пациентов с дислипидемиями. Проведен анализ показателей липидограммы, ультразвукового допплеровского исследования брахиоцефальных артерий и эхокардиографии. Представлены данные предварительного исследования генетических вариантов гена рецептора липопротеинов низкой плотности. Отмечены отягощенный наследственный семейный анамнез, изменения показателей эхокардиографических данных и атеросклеротические изменения брахиоцефальных артерий.</p></abstract><trans-abstract xml:lang="en"><p>The work presents the results of clinical, laboratory and instrumental data of 162 patients with dyslipidemia. The analysis of lipid profile, ultrasound Doppler sounding of brachiocephalic artery and echocardiography was conducted. Data of preliminary genetic alternate research of the gene of low density lipoprotein receptors is presented. Aggravated heritage family history, echocardiography data changing and atherosclerotic changes of brachiocephalic arteries are noticed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дислипидемия</kwd><kwd>гиперхолестеринемия</kwd><kwd>генетический полиморфизм</kwd><kwd>dyslipidemia</kwd><kwd>hypercholesteremia</kwd><kwd>genetic polymorphism</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO Human Genetic Programm. Familial Hypercholesterolaemia, report of a WHO consultation. // WHO/HGN/FH/CONS/98.7. - Paris; October. - 1997.</mixed-citation><mixed-citation xml:lang="en">WHO Human Genetic Programm. Familial Hypercholesterolaemia, report of a WHO consultation. // WHO/HGN/FH/CONS/98.7. - Paris; October. - 1997.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Giveira, F. 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