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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medbio</journal-id><journal-title-group><journal-title xml:lang="ru">Медико-биологические проблемы жизнедеятельности</journal-title><trans-title-group xml:lang="en"><trans-title>Medical and Biological Problems of Life Activity</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2088</issn><publisher><publisher-name>Республиканский научно-практический центр радиационной медицины и экологии человека</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">medbio-66</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ И ПРОБЛЕМНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS AND PROBLEM ARTICLES</subject></subj-group></article-categories><title-group><article-title>ХРОНИЧЕСКИЕ ИНФЕКЦИИ МОЧЕВЫВОДЯЩИХ ПУТЕЙ: СОСТОЯНИЕ ПРОБЛЕМЫ</article-title><trans-title-group xml:lang="en"><trans-title>CHRONIC URINARY TRACT INFECTIONS: THE CONDITION OF THE PROBLEM</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярец</surname><given-names>Ю. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yarets</surname><given-names>Y. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шевченко</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shevchenko</surname><given-names>N. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Старовойтов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Starovoitov</surname><given-names>A. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Русаленко</surname><given-names>М. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Rusalenko</surname><given-names>M. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГУ "РНПЦ радиационной медицины и экологии человека"</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>02</day><month>03</month><year>2023</year></pub-date><volume>0</volume><issue>2</issue><fpage>18</fpage><lpage>23</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ярец Ю.И., Шевченко Н.И., Старовойтов А.А., Русаленко М.Г., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Ярец Ю.И., Шевченко Н.И., Старовойтов А.А., Русаленко М.Г.</copyright-holder><copyright-holder xml:lang="en">Yarets Y..., Shevchenko N..., Starovoitov A..., Rusalenko M...</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medbio.ejournal.by/jour/article/view/66">https://medbio.ejournal.by/jour/article/view/66</self-uri><abstract><p>Представлен анализ литературных данных, касающихся проблемы инфекций мочевыводящих путей. Освящены вопросы хронических рецидивирующих инфекций, проанализированы этиология и некоторые моменты патогенеза, а также причины увеличения доли хронических форм в общей структуре инфекций мочевыводящих путей. Особое внимание уделено проблеме диагностики различных проявлений инфекционного процесса, трудностям в лечении, которые связаны с развитием антибиотикорезистентности уропатогенов</p></abstract><trans-abstract xml:lang="en"><p>The overview of foreign and domestic literature data dedicated to the problem of the upper urinary tract infections was carried out. The issues of chronic recurrent infections is individually highlighted. The causes and some pathogenesis features were analysed, as well as the reasons for the increase of the chronic conditions percentage in the general structure of infections. Particular attention was paid to the diagnosis problem of the different symptoms of infection process in urinary tract and to the difficulties of the treatment connected with antibiotic resistance development of the uropathogens.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>инфекции мочевыводящих путей</kwd><kwd>хронический пиелонефрит</kwd><kwd>антибиотикорезистентность</kwd><kwd>urinary tract infections</kwd><kwd>chronic pyelonephritis</kwd><kwd>antibiotic resistance</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Урологические инфекции / под. ред. N. Grabe. - Европейская ассоциация урологов, 2011. - 115 с.</mixed-citation><mixed-citation xml:lang="en">Урологические инфекции / под. ред. N. 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