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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medbio</journal-id><journal-title-group><journal-title xml:lang="ru">Медико-биологические проблемы жизнедеятельности</journal-title><trans-title-group xml:lang="en"><trans-title>Medical and Biological Problems of Life Activity</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2088</issn><publisher><publisher-name>Республиканский научно-практический центр радиационной медицины и экологии человека</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.58708/2074-2088.2026-3(39)-94-100</article-id><article-id custom-type="elpub" pub-id-type="custom">medbio-541</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Сцинтиграфическая оценка гипоксии миокарда у пациентов с хронической обструктивной болезнью лёгких на разборе клинического случая</article-title><trans-title-group xml:lang="en"><trans-title>Scintigraphic assessment of myocardial hypoxia in patients with chronic obstructive pulmonary disease in a clinical case study</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-7881-3460</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Родина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Rodzina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><email xlink:type="simple">Rodinae2016@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7496-6164</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гавриленко</surname><given-names>Д. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Haurylenka</surname><given-names>D. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><email xlink:type="simple">dm.gavrilenko891@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корженевская</surname><given-names>Н. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Karzhaneuskaya</surname><given-names>N. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><email xlink:type="simple">gancor@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3061-5324</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зыблева</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zybleva</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><email xlink:type="simple">zyb-svetlana@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романива</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Romaniva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><email xlink:type="simple">romanivaok@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Саливончик</surname><given-names>А. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Salivontchik</surname><given-names>A. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><email xlink:type="simple">salivonchikAP@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тихонова</surname><given-names>Е. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsikhonova</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><email xlink:type="simple">Stusha25@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГУ «РНПЦ радиационной медицины и экологии человека»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>01</day><month>11</month><year>2026</year></pub-date><volume>0</volume><issue>3</issue><fpage>94</fpage><lpage>100</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Родина Е.В., Гавриленко Д.И., Корженевская Н.И., Зыблева С.В., Романива О.А., Саливончик А.П., Тихонова Е.С., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Родина Е.В., Гавриленко Д.И., Корженевская Н.И., Зыблева С.В., Романива О.А., Саливончик А.П., Тихонова Е.С.</copyright-holder><copyright-holder xml:lang="en">Rodzina A.V., Haurylenka D.I., Karzhaneuskaya N.I., Zybleva S.V., Romaniva A.A., Salivontchik A.P., Tsikhonova K.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medbio.ejournal.by/jour/article/view/541">https://medbio.ejournal.by/jour/article/view/541</self-uri><abstract><p>ЭКГ-синхронизированная перфузионная однофотонная компьютерная томография миокарда с физической нагрузкой — перспективная современная методика для оценки перфузии миокарда. Данный метод позволяет выявить перфузионные дефекты, оценить регионарную и глобальную сократимость, определить жизнеспособность кардиомиоцитов в зоне ишемии, а также охарактеризовать метаболические и иннервационные процессы в миокарде. Целью данной статьи является оценка на основании клинического случая роли однофотонной эмиссионной компьютерной томографии с физической нагрузкой для оценки нарушении в диагностике ишемической болезни сердца у пациентов с хронической обструктивной болезнью лёгких. Полученные данные показывают, что применение однофотонной перфузионной сцинтиграфия миокарда с нагрузкой у пациентов с ХОБЛ клинически обосновано: оно обеспечивает надёжную стратификацию риска ИБС, позволяет верифицировать дисфункцию правого желудочка и может служить руководством к выбору тактики реваскуляризации, что особенно актуально у пациентов со значимой лёгочной патологии.</p></abstract><trans-abstract xml:lang="en"><p>Exercise-guided single-photon emission computed tomography (SPECT) of the myocardium is a promising modern technique for assessing myocardial perfusion. This method allows for the evaluation of regional and global contractility, the identification of perfusion defects, the determination of cardiomyocyte viability in the ischemic zone, and the characterization of metabolic and innervational processes in the myocardium. The objective of this article is to evaluate, based on a clinical case, the role of exercise-guided SPECT for assessing abnormalities in the diagnosis of coronary artery disease in patients with chronic obstructive pulmonary disease. The obtained data show that the use of single-photon myocardial perfusion scintigraphy with stress in patients with COPD is clinically justified: it provides reliable stratification of the risk of coronary heart disease, allows verification of right ventricular dysfunction and can serve as a guide for the choice of revascularization tactics, which is especially important in patients with significant pulmonary pathology.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая обструктивная болезнь лёгких</kwd><kwd>ишемическая болезнь сердца</kwd><kwd>ЭКГ-синхронизированная перфузионная ОФЭКТ миокарда в покое и с физической нагрузкой</kwd><kwd>коронарография</kwd><kwd>КТ коронарография</kwd><kwd>эхокардиография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic obstructive pulmonary disease</kwd><kwd>ischemic heart disease</kwd><kwd>ECGsynchronized myocardial perfusion SPECT at rest and with exercise</kwd><kwd>coronary angiography</kwd><kwd>CT coronary angiography</kwd><kwd>echocardiography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Глобальная стратегия диагностики, лечения и профилактики хронической обструктивной болезни легких: отчет за 2025 год / Глобальная инициатива по хронической обструктивной болезни легких. – 2025. – URL: https://goldcopd.org/2025-gold-report (дата обращения: 24.02.2026).</mixed-citation><mixed-citation xml:lang="en">Глобальная стратегия диагностики, лечения и профилактики хронической обструктивной болезни легких: отчет за 2025 год / Глобальная инициатива по хронической обструктивной болезни легких. – 2025. – URL: https://goldcopd.org/2025-gold-report (дата обращения: 24.02.2026).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Sin, D. 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