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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medbio</journal-id><journal-title-group><journal-title xml:lang="ru">Медико-биологические проблемы жизнедеятельности</journal-title><trans-title-group xml:lang="en"><trans-title>Medical and Biological Problems of Life Activity</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2088</issn><publisher><publisher-name>Республиканский научно-практический центр радиационной медицины и экологии человека</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.58708/2074-2088.2026-2(38)-88-95</article-id><article-id custom-type="elpub" pub-id-type="custom">medbio-527</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIENCE EXCHANGE</subject></subj-group></article-categories><title-group><article-title>Опыт гибридного лечения инфаркта головного мозга в острейшем периоде инсульта</article-title><trans-title-group xml:lang="en"><trans-title>Experience of hybrid treatment of cerebral infarction in the acute phase of ischemic stroke</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-2388-2205</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дроздов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Drozdov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><email xlink:type="simple">leshadrozdov96@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Быстренков</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bystrenkov</surname><given-names>А. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Повелица</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Povelitsa</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрельченя</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Strelchenya</surname><given-names>А. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Каплан</surname><given-names>М. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kaplan</surname><given-names>M. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Доманцевич</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Domantsevich</surname><given-names>V. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>УЗ «Гомельская университетская клиника — областной госпиталь инвалидов ВОВ»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>УО «Гомельский государственный медицинский университет»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-3"><institution>УЗ «Гомельская университетская клиника — областной госпиталь инвалидов ВОВ»; УО «Гомельский государственный медицинский университет»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-4"><institution>ГУ «РНПЦ радиационной медицины и экологии человека»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>07</day><month>08</month><year>2026</year></pub-date><volume>0</volume><issue>2</issue><fpage>88</fpage><lpage>95</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Дроздов А.В., Быстренков А.В., Повелица Э.А., Стрельченя А.В., Каплан М.Л., Доманцевич В.А., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Дроздов А.В., Быстренков А.В., Повелица Э.А., Стрельченя А.В., Каплан М.Л., Доманцевич В.А.</copyright-holder><copyright-holder xml:lang="en">Drozdov A.V., Bystrenkov А.V., Povelitsa E.A., Strelchenya А.V., Kaplan M.L., Domantsevich V.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medbio.ejournal.by/jour/article/view/527">https://medbio.ejournal.by/jour/article/view/527</self-uri><abstract><p>В статье представлен опыт на примере пяти гибридных операций в острейшем периоде ишемического инсульта, сочетающих эндоваскулярную тромбаспирацию из среднемозговой артерии с открытой каротидной эндартерэктомией (КЭАЭ) экстракраниального сегмента внутренней сонной артерии (ВСА) с оценкой результативности выполненных операций по шкале визуализации восстановления перфузии при ишемическом инсульте Thrombolysis in Cerebral Infarction score(TICI) и по модифицированной шкале Рэнкин (mRs) при поступлении и в течение 90 дней от начала заболевания. Интраоперационно реканализации интракраниальных артерий удалось добиться в 100% случаев с восстановлением неврологического дефицита менее 2 баллов по mRs у четырёх пациентов.</p></abstract><trans-abstract xml:lang="en"><p>The article presents an experience based on five hybrid procedures performed in the acute phase of ischemic stroke, combining endovascular aspiration thrombectomy from the middle cerebral artery with open carotid endarterectomy of the extracranial segment of the internal carotid artery, with an assessment of the effectiveness of the procedures using the Thrombolysis in Cerebral Infarction scale and the modified Rankin Scale (mRS) at admission and within 90 days from disease onset. Intraoperatively, recanalization of the intracranial arteries was achieved in 100% of cases, with recovery of the neurological deficit to less than 2 points on the mRS.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>каротидная эндатерэктомия</kwd><kwd>тромбаспирация</kwd><kwd>инфаркт головного мозга</kwd><kwd>гибридные операции</kwd></kwd-group><kwd-group xml:lang="en"><kwd>endarterectomy</kwd><kwd>thrombaspiration</kwd><kwd>cerebral infarction</kwd><kwd>hybrid operations</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Paciaroni, M. The concept of ischemic penumbra in acute stroke and therapeutic opportunities / M. Paciaroni, V. Caso, G. Agnelli // Eur Neurol. – 2009. – Vol. 61, No. 6. – P. 321–330. – DOI: 10.1159/000210544.</mixed-citation><mixed-citation xml:lang="en">Paciaroni, M. The concept of ischemic penumbra in acute stroke and therapeutic opportunities / M. 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