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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medbio</journal-id><journal-title-group><journal-title xml:lang="ru">Медико-биологические проблемы жизнедеятельности</journal-title><trans-title-group xml:lang="en"><trans-title>Medical and Biological Problems of Life Activity</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2088</issn><publisher><publisher-name>Республиканский научно-практический центр радиационной медицины и экологии человека</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.58708/2074-2088.2025-3(35)-81-88</article-id><article-id custom-type="elpub" pub-id-type="custom">medbio-467</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Синдром внутрисосудистой абсорбции как осложнение оперативной гистероскопии</article-title><trans-title-group xml:lang="en"><trans-title>Intravascular absorption syndrome as a complication of surgical hysteroscopy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подгорная</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Podgornaya</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарко</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaharko</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурашко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Murashko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калачев</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalachеv</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГУ «РНПЦ радиационной медицины и экологии человека»</institution></aff><aff xml:lang="en"><institution>ГУ «РНПЦ радиационной медицины и экологии человека»</institution></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>УО «Гомельский государственный медицинский университет»</institution></aff><aff xml:lang="en"><institution>УО «Гомельский государственный медицинский университет»</institution></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>20</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>81</fpage><lpage>88</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Подгорная А.С., Захарко А.Ю., Мурашко О.В., Калачев В.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Подгорная А.С., Захарко А.Ю., Мурашко О.В., Калачев В.Н.</copyright-holder><copyright-holder xml:lang="en">Podgornaya A.S., Zaharko A.Y., Murashko O.V., Kalachеv V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medbio.ejournal.by/jour/article/view/467">https://medbio.ejournal.by/jour/article/view/467</self-uri><abstract><p>Статья посвящена наиболее грозному осложнению гистерорезектоскопии — синдрому внутрисосудистой абсорбции. Проведён анализ литературных данных с определением причин возникновения синдрома, клинических проявлений, диагностических аспектов и лечебной тактики. Частота встречаемости синдрома составляет 0,2 процента. Ведущим патогенетическим механизмом являются электролитные нарушения. Клинические проявления характеризуются нарастанием неврологической симптоматики, которая зависит от уровня натрия в крови и может привести к отёку лёгких, отёку головного мозга с возможным летальным исходом. Основным принципом лечения является коррекция электролитных нарушений, а именно натрия. При развитии острого повреждения почек – своевременное лечение с использованием гемодиализа, а в случае сердечной недостаточности – экстракорпоральной мембранной оксигенации. Лечение проводится в условиях отделения интенсивной терапии с участием мультидисциплинарной бригады.</p></abstract><trans-abstract xml:lang="en"><p>The article is devoted to the most formidable complication of hysteroresectoscopy – intravascular absorption syndrome. The analysis of literary data with determination of the causes of the syndrome, clinical manifestations, diagnostic aspects and treatment tactics is carried out. The frequency of occurrence of the syndrome is 0,20%. Clinical manifestations are characterized by the increase of neurological symptoms, which depend on the level of sodium in the blood and can lead to pulmonary edema, cerebral edema with possible lethal outcome. The main principle of treatment is correction of electrolyte disturbances, namely sodium. In case of development of acute kidney injury – timely treatment using hemodialysis, and in case of heart failure – extracorporeal membrane oxygenation.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>монополярная и биполярная гистерорезектоскопия</kwd><kwd>синдром внутрисосудистой абсорбции</kwd><kwd>осложнения гистероскопии</kwd><kwd>интравазация жидких расширяющих сред</kwd><kwd>электролитные нарушения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>monopolar and bipolar hysteroresectoscopy</kwd><kwd>intravascular absorption syndrome</kwd><kwd>hysteroscopy complications</kwd><kwd>intravasation of liquid diluents</kwd><kwd>electrolyte disorders</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Давыдов, А.И. Оперативная гистероскопия / А.И. Давыдов, А.Н. Стрижаков. – Москва: Династия, 2015. – 196 с.</mixed-citation><mixed-citation xml:lang="en">Давыдов, А.И. 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