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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medbio</journal-id><journal-title-group><journal-title xml:lang="ru">Медико-биологические проблемы жизнедеятельности</journal-title><trans-title-group xml:lang="en"><trans-title>Medical and Biological Problems of Life Activity</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2088</issn><publisher><publisher-name>Республиканский научно-практический центр радиационной медицины и экологии человека</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.58708/2074-2088.2024-2(32)-95-99</article-id><article-id custom-type="elpub" pub-id-type="custom">medbio-397</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Анализ случаев гладкомышечных опухолей матки с неопределенным злокачественным потенциалом (STUMP) в ГУ «РНПЦ радиационной медицины и экологии человека»</article-title><trans-title-group xml:lang="en"><trans-title>Analysis of cases of smooth muscle tumors of the uterus with uncertain malignant potential (STUMP) at the SI «Republican research center for radiation medicine and human ecology»</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарко</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaharko</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Врач-акушер-гинеколог, к.м.н.</p><p>г. Гомель</p></bio><email xlink:type="simple">annazakharko@tut.by</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Подгорная</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Podgornaya</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мурашко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Murashko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жандаров</surname><given-names>М. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhandarov</surname><given-names>М. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ромбальская</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Rombalskaya</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>г. Минск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>ГУ «РНПЦ радиационной медицины и экологии человека»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>УО «Белорусский государственный медицинский университет»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>04</day><month>10</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><fpage>95</fpage><lpage>99</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Захарко А.Ю., Подгорная А.С., Мурашко О.В., Жандаров М.Ю., Ромбальская А.Р., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Захарко А.Ю., Подгорная А.С., Мурашко О.В., Жандаров М.Ю., Ромбальская А.Р.</copyright-holder><copyright-holder xml:lang="en">Zaharko A.Y., Podgornaya A.S., Murashko O.V., Zhandarov М.Y., Rombalskaya A.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medbio.ejournal.by/jour/article/view/397">https://medbio.ejournal.by/jour/article/view/397</self-uri><abstract><p>Статья посвящена анализу случаев гладкомышечных опухолей матки с неопределенным злокачественным потенциалом (STUMP), выявленных в ГУ «РНПЦ РМиЭЧ» в период с 2017 по 2024 год. Удельный вес опухоли среди всех пациенток, прооперированных в обозначенный период по поводу лейомиомы, равен 0,38%. Средний возраст составил 43 (32–45) года. Клинические проявления заболевания и ультразвуковые характеристики опухоли идентичны лейомиоме матки. Патогистологические критерии STUMP сложны для выявления и редко устанавливались интраоперационно (20% случаев). За период наблюдения не выявлено случаев рецидивирования и метастазирования опухоли. Учитывая редкость опухоли, сложности предоперационной диагностики, отсутствовал единый протокол ведения пациентов.</p></abstract><trans-abstract xml:lang="en"><p>The article is devoted to the analysis of cases of uterine smooth muscle tumors with undetermined malignant potential (STUPM), identified in the State Institution «Republican Scientific and Practical Center of Russian Medical Research and Emergencies» in the period from 2017 to 2024. The proportion of tumor among all patients operated on for leiomyoma during the indicated period was 0,38%. The average age was 43 (32-45) years. Clinical manifestations of the disease and ultrasound characteristics of the tumor were identical to uterine leiomyoma. Pathological criteria for STUMP are difficult to identify and were rarely established intraoperatively (20% of cases). During the observation period, no cases of tumor recurrence or metastasis were detected. Considering the rarity of the tumor and the complexity of preoperative diagnosis, there was no uniform protocol for patient management.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гладкомышечные опухоли</kwd><kwd>миома матки</kwd><kwd>гладкомышечные опухоли с неопределенным злокачественным потенциалом</kwd><kwd>STUMP</kwd><kwd>саркома</kwd></kwd-group><kwd-group xml:lang="en"><kwd>smooth muscle tumors</kwd><kwd>uterine fibroids</kwd><kwd>smooth muscle tumors of uncertain malignant potential</kwd><kwd>STUMP</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Hughes, L. STUMP, a surprise finding in a large fibroid uterus in a 20-year-old woman / L. Hughes, A. Roex, A. Parange // Int. J. Women’s Health. – 2018. – Vol.10. – P. 211-214.</mixed-citation><mixed-citation xml:lang="en">Hughes, L. STUMP, a surprise finding in a large fibroid uterus in a 20-year-old woman / L. 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