medbioМедико-биологические проблемы жизнедеятельностиMedical and Biological Problems of Life Activity2074-2088Республиканский научно-практический центр радиационной медицины и экологии человека10.58708/2074-2088.2024-1(31)-30-39medbio-369Research ArticleОБЗОРЫ И ПРОБЛЕМНЫЕ СТАТЬИREVIEWS AND PROBLEM ARTICLESНадпочечниковая недостаточность после оперативного лечения новообразований надпочечников: эпидемиология, диагностика, лечение и профилактикаAdrenal insufficiency after surgical treatment of adrenal neoplasms: epidemiology, diagnosis, treatment and preventionhttps://orcid.org/0000-0002-2867-5099ЧулковА. А.ChulkovА. А.

г. Гомель

arschulkov@gmail.comДундаровЗ. А.DundarovZ. А.

г. Гомель

ВеличкоА. В.VelichkoА. V.

г. Гомель

ЗыблевС. Л.ZyblevS. L.

г. Гомель

НавменоваЯ. Л.NavmenovaYa. L.

г. Гомель

ГУ «РНПЦ радиационной медицины и экологии человека»BelarusУО «Гомельский государственный медицинский университет»Belarus202411052024013039Copyright © Чулков А.А., Дундаров З.А., Величко А.В., Зыблев С.Л., Навменова Я.Л., 20242024Чулков А.А., Дундаров З.А., Величко А.В., Зыблев С.Л., Навменова Я.Л.Chulkov А.А., Dundarov Z.А., Velichko А.V., Zyblev S.L., Navmenova Y.L.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medbio.ejournal.by/jour/article/view/369

В статье представлен обзор проблемы послеоперационной надпочечниковой недостаточности (НН) у пациентов после односторонней адреналэктомии. Описана клиническая картина НН и последствия при несвоевременном оказании помощи. Систематизирована и освещена распространенность заболевания при различных вариантах новообразований надпочечников после их хирургического лечения. Приведены предикторы развития НН и современные лабораторные методы для её диагностики. Также изучен и освещен вопрос возможности фармакотерапии данной патологии на сегодняшний день. И что более важно, описаны направления профилактики надпочечниковой недостаточности у пациентов с новообразованиями надпочечников, которым показано хирургическое лечение.

The article provides an overview of the problem of postoperative adrenal insufficiency (AI) in patients after unilateral adrenalectomy. The clinical picture of AI and the consequences of untimely provision of medical care are described. The prevalence of the disease in various types of adrenal neoplasms after their surgical treatment is systematized and highlighted. Predictors of the AI development and modern laboratory methods for its diagnosis are presented. The issue of the current possibility of pharmacotherapy for this pathology has also been studied and highlighted. And more importantly, directions for the prevention of adrenal insufficiency in patients with adrenal neoplasms who are indicated for surgical treatment are described.

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The authors declare that there are no conflicts of interest present.