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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">medbio</journal-id><journal-title-group><journal-title xml:lang="ru">Медико-биологические проблемы жизнедеятельности</journal-title><trans-title-group xml:lang="en"><trans-title>Medical and Biological Problems of Life Activity</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-2088</issn><publisher><publisher-name>Республиканский научно-практический центр радиационной медицины и экологии человека</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.58708/2074-2088.2024-2(32)-105-110</article-id><article-id custom-type="elpub" pub-id-type="custom">medbio-368</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКАЯ МЕДИЦИНА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL MEDICINE</subject></subj-group></article-categories><title-group><article-title>Замещение дефектов наружного носа с использованием хрящевых аллографтов: послеоперационные осложнения и косметические результаты</article-title><trans-title-group xml:lang="en"><trans-title>Nasal defect reconstruction using cartilage allografts: postoperative complications and cosmetic outcomes</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9256-2910</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Доцент кафедры онкологии, кандидат медицинских наук</p><p>г. Гомель</p></bio><email xlink:type="simple">srgivgm@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хоров</surname><given-names>О. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Khorov</surname><given-names>O. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Заведующий кафедрой оториноларингологии ГрГМУ, доктор медицинских наук, профессор</p><p>г. Гродно</p></bio><email xlink:type="simple">khorov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юрковский</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Yurkovsky</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Заведующий кафедрой лучевой диагностики и лучевой терапии ГомГМУ, доктор медицинских наук, доцент</p><p>г. Гродно</p></bio><email xlink:type="simple">yurkovsky@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богомаз</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogomaz</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Врач-рентгенолог</p><p>г. Гомель</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>УО «Гомельский государственный медицинский университет»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>УО «Гродненский государственный медицинский университет»</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-3"><institution>УО «Гомельский областной клинический онкологический диспансер»</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>01</day><month>10</month><year>2024</year></pub-date><volume>0</volume><issue>2</issue><fpage>105</fpage><lpage>110</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванов С.А., Хоров О.Г., Юрковский А.М., Богомаз А.С., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Иванов С.А., Хоров О.Г., Юрковский А.М., Богомаз А.С.</copyright-holder><copyright-holder xml:lang="en">Ivanov S.A., Khorov O.G., Yurkovsky A.M., Bogomaz A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://medbio.ejournal.by/jour/article/view/368">https://medbio.ejournal.by/jour/article/view/368</self-uri><abstract><p>В статье представлено исследование результатов 73 реконструкций наружного носа с использованием аллогенных хрящевых графтов. Послеоперационные осложнения развились в 9 наблюдениях (12,3%), 2 случая (2,7%) связаны с хрящевым графтом. Пациенты и эксперты оценили косметический результат реконструкции по 5-балльной шкале. Оценки пациентов были статистически значимо выше, чем оценки экспертов для показателей «крыло носа» (р=0,001), «размер носовых отверстий» (р=0,005), «цвет кожи носа» (р=0,028), «положение носа» (р=0,028). Снижение оценок наиболее часто регистрировали для показателей «крыло носа», «спинка носа», «размер носовых отверстий», «цвет кожи носа». Приемлемый результат общего вида носа отмечен в 62 наблюдениях (84,9%). Ультразвуковое исследование и магнитно-резонансная томография наружного носа выполнены 12 пациентам через 2 года и более после реконструкции. Наличие хрящевого аллографта в месте имплантации без признаков лизиса и деформации подтверждено обоими методами. Проведенное исследование позволяет заключить, что хрящевой материал от трупных доноров может быть эффективно использован для реконструкции наружного носа.</p></abstract><trans-abstract xml:lang="en"><p>This article presents study of immediate and long-term outcomes following 73 nasal reconstruction using cartilage allografts. Postoperative complications developed in 9 cases (12,3%). Two cases (2,7%) were associated with cartilage allograft. Cosmetic outcome was evaluated minimally in 6 months after reconstruction. Patients and experts evaluated 6 particular parameters and total nasal appearance using 5-point scale. Patient scores were higher than expert scores for nasal alar (р=0,001), nostril size (р=0,005), nasal skin color (р=0,028), nasal position (р=0,028). Declined scores were more common registered for parameters nasal alar, nasal dorsum, nostril size, nasal skin color. Experts defined total nasal appearance as acceptable (4 or 5 points) in 62 cases (84,9%). Twelve patients underwent ultrasonography and magnetic resonance tomography of facial tissues in minimally 2 years after reconstruction. Cartilage allografts within reestablished nasal subunits were identified using both methods. No significant deformities and dystrophic changes were discovered. This study showed that allogeneic cadaver cartilage can be used effectively for nasal reconstruction.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>дефект наружного носа</kwd><kwd>реконструкция наружного носа</kwd><kwd>хрящевой графт</kwd><kwd>аллогенный хрящ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>nasal defect</kwd><kwd>nasal reconstruction</kwd><kwd>cartilage graft</kwd><kwd>allogeneic cartilage</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Joseph, A.W. Reconstruction of the Nose / A.W. Joseph, C. Truesdale, S.R. 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