medbioМедико-биологические проблемы жизнедеятельностиMedical and Biological Problems of Life Activity2074-2088Республиканский научно-практический центр радиационной медицины и экологии человека10.58708/2074-2088.2023-2(30)-111-116medbio-323Research ArticleКЛИНИЧЕСКАЯ МЕДИЦИНАCLINICAL MEDICINEФакторы снижения минеральной плотности костной ткани у детей с синдромом Шерешевского-ТернераFactors of reduced bone mineral density in children with Turner syndromeПесковаяН. А.PeskavayaN. A.

г. Минск

tavgena@tut.byСолнцеваА. В.SolntsavaA. V.

г. Минск

ang_solntseva@mail.ruГУ «РЦ медицинской реабилитации и бальнеолечения»BelarusУО «Белорусский государственный медицинский университет»; ГУ «РНПЦ детской онкологии, гематологии и иммунологии»Belarus20232808202302111116Copyright © Песковая Н.А., Солнцева А.В., 20232023Песковая Н.А., Солнцева А.В.Peskavaya N.A., Solntsava A.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://medbio.ejournal.by/jour/article/view/323

Снижение минеральной массы костной ткани является одной из значимых соматических проблем для девочек подросткового возраста с СШТ. В публикации представлены результаты собственного исследования, в котором дана оценка состояния минеральной плотности костной ткани у детей с синдромом Шерешевского-Тернера в зависимости от возраста, варианта кариотипа, спонтанного или стимулированного начала полового развития. Установлена высокая частота дефицита минеральной плотности костной ткани у пациенток с синдромом Шерешевского-Тернера вне зависимости от наличия пубертата. Изменения плотности костной ткани реже отмечены у девочек со спонтанным пубертатом. Различия величины минеральной плотности костной ткани между пациентками с синдромом Шерешевского-Тернера и здоровыми девочками выявлены с возраста 11 лет.

Decreased bone mineral mass is one of the significant somatic problems for adolescents with Turner syndrome. The results of our own study, which estimates the state of bone mineral density in children with Turner syndrome depending on age, karyotype variant, spontaneous or stimulated onset of sexual development are present in the publication. A high frequency of bone mineral density deficiency in patients with Turner syndrome was established, regardless of the presence of puberty. Changes in bone density in girls with spontaneous puberty are less common. The difference in bone mineral density between patients with Turner syndrome and the control group from the age of 11 years was shown. Positive effect of replacement estrogen therapy on bone tissue condition in Turner syndrome is shown.

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The authors declare that there are no conflicts of interest present.